| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human,Mouse,Rat |
| Host species | Mouse |
| Applications | WB-Ce,WB-Ti,IHC-P |
| Brand: | Abnova |
| Reference: | MAB6243 |
| Product name: | CASP7 monoclonal antibody, clone 25B881.1 |
| Product description: | Mouse monoclonal antibody raised against recombinant CASP7. |
| Clone: | 25B881.1 |
| Isotype: | IgG1 |
| Gene id: | 840 |
| Gene name: | CASP7 |
| Gene alias: | CMH-1|ICE-LAP3|MCH3 |
| Gene description: | caspase 7, apoptosis-related cysteine peptidase |
| Immunogen: | Recombinant protein corresponding to human CASP7. |
| Protein accession: | NP_001081408 |
| Form: | Liquid |
| Recommend dilutions: | Western Blot (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS (0.05% sodium azide) |
| Storage instruction: | Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Antigen species / target species: | Human |
| Reactivity: | Human,Mouse,Rat |
| Application image: | ![]() |
| Application image note: | Western blot analysis of CASP7 in Jurkat cells using CASP7 monoclonal antibody, clone 25B881.1 (Cat #MAB6243) at 1 ug/mL. Cells were treated with 2 uM staurosporine for different time periods. CASP7 activation is detected in western blots by the presence of CASP7 cleavage fragments. The antibody detected both pro (full-length) and active (cleaved) CASP7, depending on the treatment time points. A basal level of endogenous intermediate CASP7 can be see in untreated Jurkat cells. |
| Applications: | WB-Ce,WB-Ti,IHC-P |
| Shipping condition: | Dry Ice |
| Publications: | Mch3, a novel human apoptotic cysteine protease highly related to CPP32.Fernandes-Alnemri T, Takahashi A, Armstrong R, Krebs J, Fritz L, Tomaselli KJ, Wang L, Yu Z, Croce CM, Salveson G, et al.. Cancer Res. 1995 Dec 15;55(24):6045-52. |