| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Mouse |
| Applications | WB,IHC-P |
| Brand: | Abnova |
| Reference: | MAB5333 |
| Product name: | GZMA monoclonal antibody, clone GA6 |
| Product description: | Mouse monoclonal antibody raised against recombinant GZMA. |
| Clone: | GA6 |
| Isotype: | IgG1 |
| Gene id: | 3001 |
| Gene name: | GZMA |
| Gene alias: | CTLA3|HFSP |
| Gene description: | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) |
| Immunogen: | Recombinant protein corresponding to human GZMA. |
| Form: | Liquid |
| Recommend dilutions: | Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In Tris (0.09% sodium azide) |
| Storage instruction: | Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Antigen species / target species: | Human |
| Specificity: | This antibody recognizes Granzyme A, a 60kD disulphide-linked homodimeric protein expressed in cytoplasmic granules of cytotoxic lymphocytes. The biological function of Granzyme A is unclear. It would appear that the molecule may have a role in the induction of apoptosis via its activity as a serine protease, but this would seem to be subsidiary to the role of Granzyme B. Granzyme A deficient mice are indistinguishable from normal animals in their response to infection. |
| Reactivity: | Human |
| Applications: | WB,IHC-P |
| Shipping condition: | Dry Ice |