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Data sheet of ITGA5 monoclonal antibody, clone CLB-705
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Clonality | Monoclonal |
| Host species | Mouse |
| Applications | IF,Flow Cyt |
More info about ITGA5 monoclonal antibody, clone CLB-705
| Product description: | Mouse monoclonal antibody raised against native ITGA5. |
| Clone: | CLB-705 |
| Isotype: | IgG2b |
| Gene id: | 3678 |
| Gene name: | ITGA5 |
| Gene alias: | CD49e|FNRA|VLA5A |
| Gene description: | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| Immunogen: | Native purified from U937 cell line. |
| Form: | Liquid |
| Recommend dilutions: | The optimal working dilution should be determined by the end user. |
| Storage buffer: | In 20 mM Tris, 150 mM NaCl, pH 8.0 (10 mg BSA, 0.001% thimerosal) |
| Storage instruction: | Store at 4°C. |
| Note: | This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Specificity: | The monoclonal antibody is directed against the CD49e-antigen, molecular weights: 17, 130 kD, (GP Ic or VLA-5 alpha-chain), which can form distinct complexes with either the CD29-antigen (GP IIa or VLA beta-chain), resulting in the VLA-5 (alpha-5, beta-1) complex which is expressed on human platelets. Platelet VLA-5 functions as a fibronectin receptor and platelet adhesion to fibronectin is inhibited by this antibody. The monoclonal antibody reacts with platelets and monocytes. It reacts weakly with T-cells and granulocytes and with various cell types of non-hemopoietic origin. |
| Size: | 1 mL |
| Shipping condition: | Blue Ice |