| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Clonality | Monoclonal |
| Host species | Mouse |
| Applications | IP,IHC-Fr,Flow Cyt |
| Product description: | Mouse monoclonal antibody raised against native CD180. |
| Clone: | MHR73 |
| Isotype: | IgG1 |
| Gene id: | 4064 |
| Gene name: | CD180 |
| Gene alias: | LY64|Ly78|MGC126233|MGC126234|RP105 |
| Gene description: | CD180 molecule |
| Immunogen: | Native purified CD180 from M12HRP cell line. |
| Form: | Liquid |
| Recommend dilutions: | Flow Cytometry (10ul of the suggested working dilution (1:50-1:100) to label 106 cells in 100ul) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS (0.09% sodium azide) |
| Storage instruction: | Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Specificity: | This antibody recognizes human CD180 (RP105) a 105kD type 1 transmembrane protein, which belongs to the toll-like receptor family. CD180 is primarily expressed in mature peripheral B cells and is thought to play a role in the innate immune response to bacterial lipopolysaccharide, through co-operation with MD-1 and TLR4. Cross linking of CD180 with clone MHR73 has been reported to induce resistance against irradiation induced apoptosis, B-cell proliferation and up-regulation of a co-stimulatory molecule CD80. |
| Size: | 200 ug |
| Shipping condition: | Dry Ice |