| Brand: | Abnova |
| Reference: | MAB5248 |
| Product name: | CEACAM5 monoclonal antibody, clone CLB-139 |
| Product description: | Mouse monoclonal antibody raised against native CEACAM5. |
| Clone: | CLB-139 |
| Isotype: | IgG1 |
| Gene id: | 1048 |
| Gene name: | CEACAM5 |
| Gene alias: | CD66e|CEA|DKFZp781M2392 |
| Gene description: | carcinoembryonic antigen-related cell adhesion molecule 5 |
| Immunogen: | Native purified CEACAM5 from human granulocytes. |
| Form: | Liquid |
| Recommend dilutions: | The optimal working dilution should be determined by the end user. |
| Storage buffer: | In 20 mM Tris, 150 mM NaCl, pH 8.0 (10 mg BSA, 0.001% thimerosal) |
| Storage instruction: | Store at 4°C. |
| Note: | This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Antigen species / target species: | Human |
| Specificity: | The monoclonal antibody is directed against the CD66e-antigen, a 180-200 kD phosphoprotein, 90 kD PI-linked protein, which is expressed on mature human granulocytes. After activation of the granulocutes, expression the antigen is strongly increased. It reacts with 100% of mature human peripheral granulocytes. The monoclonal antibody reacts weakly with malignant cells of patients with B-cell derived chronic lymphoid leukemia (CLL). The monoclonal antibody does not react with normal human peripheral B-cells, T-cells, monocytes and platelets. In immunohistology This antibody reacts with a subpopulation of tissue macrophages and the Carcino Embryonic Antigen (CEA) expressed on colon carcinoma and other carcinomas. |
| Reactivity: | Human |
| Applications: | IF,Flow Cyt |
| Shipping condition: | Blue Ice |