| Brand: | Abnova |
| Reference: | MAB4919 |
| Product name: | Synpo monoclonal antibody, clone G1D4 |
| Product description: | Mouse monoclonal antibody raised against native Synpo. |
| Clone: | G1D4 |
| Isotype: | IgG1 |
| Gene id: | 60324 |
| Gene name: | Synpo |
| Gene alias: | - |
| Gene description: | synaptopodin |
| Immunogen: | Native purified Synpo from rat kidney glomeruli. |
| Form: | Liquid |
| Recommend dilutions: | The optimal working dilution should be determined by the end user. |
| Storage buffer: | In buffer containing 0.01% sodium azide |
| Storage instruction: | Store at 4°C. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Antigen species / target species: | Rat |
| Specificity: | Recognizes differentiated podocytes (glomerular visceral epithelial cells) in vivo and in vitro (weaker additional reaction with arterial endothelial cells), co-localization with alpha-actinin. Does not react with parietal cells. Reacts with a subset of exclusively telencephalic synapses. Differentiation-dependent expression during postnatal maturation of rat brain. Differentiation-dependent expression in cultured hippocampal neurons. Reacts specifically with synaptopodin, a prolin-rich actin-binding protein with 2 binding sites for actin. Cross-reacts with human, bovine, rat, mouse, guinea pig and gerbil. Does not cross-react with rabbit, frog or chicken. |
| Reactivity: | Bovine,Guinea pig,Human,Mouse,Rat |
| Applications: | WB,IHC-Fr,IHC-P,IF |
| Shipping condition: | Blue Ice |
| Publications: | Pterostilbene and allopurinol reduce fructose-induced podocyte oxidative stress and inflammation via microRNA-377.Wang W, Ding XQ, Gu TT, Song L, Li JM, Xue QC, Kong LD Free Radic Biol Med. 2015 Mar 4. pii: S0891-5849(15)00095-7. doi: 10.1016/j.freeradbiomed.2015.02.029. |