| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Mouse |
| Applications | Flow Cyt |
| Brand: | Abnova |
| Reference: | MAB4546 |
| Product name: | ITGAM monoclonal antibody, clone MEM-174 (Biotin) |
| Product description: | Mouse monoclonal antibody raised against native ITGAM. |
| Clone: | MEM-174 |
| Isotype: | IgG2a |
| Gene id: | 3684 |
| Gene name: | ITGAM |
| Gene alias: | CD11B|CR3A|MAC-1|MAC1A|MGC117044|MO1A|SLEB6 |
| Gene description: | integrin, alpha M (complement component 3 receptor 3 subunit) |
| Immunogen: | Native purified ITGAM from human granulocytes. |
| Form: | Liquid |
| Recommend dilutions: | Flow Cytometry (1:400) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS, pH 7.2 (0.09% sodium azide) |
| Storage instruction: | Store at 4°C. Do not freeze. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Conjugate tag: | Biotin |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Antigen species / target species: | Human |
| Specificity: | This antibody recognizes CD11b antigen (Mac-1 alpha), a 165-170 KDa type I transmembrane protein mainly expressed on monocytes, granulocytes and NK-cells. The CD11b mediates neutrophil and monocyte interactions with stimulated endothelium. |
| Reactivity: | Human |
| Applications: | Flow Cyt |
| Shipping condition: | Blue Ice |
| Publications: | Sequential binding of CD11a/CD18 and CD11b/CD18 defines neutrophil capture and stable adhesion to intercellular adhesion molecule-1.Hentzen ER, Neelamegham S, Kansas GS, Benanti JA, McIntire LV, Smith CW, Simon SI. Blood. 2000 Feb 1;95(3):911-20. |