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Data sheet of TP53 monoclonal antibody, clone BP53-12 (FITC)
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human,Non-Human Primates |
| Host species | Mouse |
| Applications | IF,Flow Cyt |
More info about TP53 monoclonal antibody, clone BP53-12 (FITC)
| Brand: | Abnova |
| Reference: | MAB4528 |
| Product name: | TP53 monoclonal antibody, clone BP53-12 (FITC) |
| Product description: | Mouse monoclonal antibody raised against recombinant TP53. |
| Clone: | BP53-12 |
| Isotype: | IgG2a |
| Gene id: | 7157 |
| Gene name: | TP53 |
| Gene alias: | FLJ92943|LFS1|TRP53|p53 |
| Gene description: | tumor protein p53 |
| Immunogen: | Recombinant protein corresponding to full length human TP53. |
| Form: | Liquid |
| Concentration: | 1 mg/mL |
| Recommend dilutions: | The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS, pH 7.2 (0.09% sodium azide) |
| Storage instruction: | Store in the dark at 4°C. Do not freeze. Avoid prolonged exposure to light. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Conjugate tag: | FITC |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Antigen species / target species: | Human |
| Specificity: | This antibody recognizes defined epitope (aa 16-25) on human p53, a 50 KDa tumour suppressor found in increased amounts in a wide variety of transformed cells. |
| Reactivity: | Human,Non-Human Primates |
| Application image: |  |
| Application image note: | Confocal microscopy of human HeLa cells using TP53 monoclonal antibody, clone BP53-12 (FITC) (Cat # MAB4528). The expression of TP53 protein was enhanced by intercalating reagent. Cells were fixed and permeabilized before incubation with the TP53 monoclonal antibody, clone BP53-12 (FITC) (Cat # MAB4528). Photo provided by Dr. Hodny, Inst. of Experimental Medicine, Prague, Czech Republic. |
| Applications: | IF,Flow Cyt |
| Shipping condition: | Blue Ice |
| Publications: | p53 protein alterations in human testicular cancer including pre-invasive intratubular germ-cell neoplasia.Bartkova J, Bartek J, Lukas J, Vojtesek B, Staskova Z, Rejthar A, Kovarik J, Midgley CA, Lane DP. Int J Cancer. 1991 Sep 9;49(2):196-202. |