| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Mouse |
| Applications | WB,IP,ICC,Flow Cyt |
| Brand: | Abnova |
| Reference: | MAB4458 |
| Product name: | CD63 monoclonal antibody, clone MEM-259 (PE) |
| Product description: | Mouse monoclonal antibody raised against native CD63. |
| Clone: | MEM-259 |
| Isotype: | IgG1 |
| Gene id: | 967 |
| Gene name: | CD63 |
| Gene alias: | LAMP-3|ME491|MLA1|OMA81H|TSPAN30 |
| Gene description: | CD63 molecule |
| Immunogen: | Native purified CD63 from human T cell line HPB-ALL. |
| Form: | Liquid |
| Recommend dilutions: | Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS (0.2% BSA, 0.09% sodium azide) |
| Storage instruction: | Store in the dark at 4°C. Do not freeze. Avoid prolonged exposure to light. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Conjugate tag: | PE |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Antigen species / target species: | Human |
| Specificity: | This antibody reacts with CD63 (LAMP-3), a 40-60 KDa tetraspan glycoprotein expressed by granulocytes, platelets, T cells, monocytes/macrophages and endothelial cells. Cell surface exposition of CD63 is usually activation-dependent. |
| Reactivity: | Human |
| Applications: | WB,IP,ICC,Flow Cyt |
| Shipping condition: | Blue Ice |
| Publications: | Expression of tetraspan protein CD63 activates protein-tyrosine kinase (PTK) and enhances the PTK-induced inhibition of ROMK channels.Lin D, Kamsteeg EJ, Zhang Y, Jin Y, Sterling H, Yue P, Roos M, Duffield A, Spencer J, Caplan M, Wang WH. J Biol Chem. 2008 Mar 21;283(12):7674-81. Epub 2008 Jan 22. |