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| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human,Non-Human Primates |
| Host species | Mouse |
| Applications | IP,Flow Cyt |
| Brand: | Abnova |
| Reference: | MAB4361 |
| Product name: | FCGR3A monoclonal antibody, clone LNK16 (PE) |
| Product description: | Mouse monoclonal antibody raised against native FCGR3A. |
| Clone: | LNK16 |
| Isotype: | IgG1 |
| Gene id: | 2214 |
| Gene name: | FCGR3A |
| Gene alias: | CD16|CD16A|FCG3|FCGR3|FCGRIII|FCR-10|FCRIII|FCRIIIA|IGFR3 |
| Gene description: | Fc fragment of IgG, low affinity IIIa, receptor (CD16a) |
| Immunogen: | Native purified FCGR3A from normal human peripheral blood granulocytes. |
| Form: | Liquid |
| Recommend dilutions: | Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS (0.2% BSA, 0.09% sodium azide) |
| Storage instruction: | Store in the dark at 4°C. Do not freeze. Avoid prolonged exposure to light. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Conjugate tag: | PE |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Antigen species / target species: | Human |
| Specificity: | This antibody reacts with CD16, a low affinity receptor for aggregated IgG (FcgammaRIII antigen). CD16 exists in two different isoforms: CD16a (FcgammaRIIIA; 50-65 KDa; expressed on NK-cells, monocytes and macrophages) and CD16b (FcgammaRIIIB; 48 KDa; mainly expressed on neutrophils). |
| Reactivity: | Human,Non-Human Primates |
| Application image: | ![]() |
| Application image note: | Surface staining of human peripheral blood cells with FCGR3A monoclonal antibody, clone LNK16 (PE) (Cat # MAB4361). |
| Applications: | IP,Flow Cyt |
| Shipping condition: | Blue Ice |
| Publications: | IgE-mediated activation of NK cells through Fc gamma RIII.Arase N, Arase H, Hirano S, Yokosuka T, Sakurai D, Saito T. J Immunol. 2003 Mar 15;170(6):3054-8. |