| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Mouse |
| Applications | Flow Cyt |
| Brand: | Abnova |
| Reference: | MAB3874 |
| Product name: | PTPRC monoclonal antibody, clone MEM-143 |
| Product description: | Mouse monoclonal antibody raised against native PTPRC. |
| Clone: | MEM-143 |
| Isotype: | IgG1 |
| Gene id: | 5788 |
| Gene name: | PTPRC |
| Gene alias: | B220|CD45|CD45R|GP180|LCA|LY5|T200 |
| Gene description: | protein tyrosine phosphatase, receptor type, C |
| Immunogen: | Native purified PTPRC from human peripheral blood lymphocytes. |
| Form: | Liquid |
| Recommend dilutions: | The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS, pH 7.4 (0.09% sodium azide) |
| Storage instruction: | Store at 4°C. Do not freeze. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Antigen species / target species: | Human |
| Specificity: | This antibody reacts with a protein determinant of CD45RB, a 180-240 KDa singlechain type I membrane glycoprotein, variant of CD45 (CD45RB isoform). CD45RB isexpressed on a subset of T lymphocytes, B lymphocytes, monocytes, macrophages, granulocytes and dendritic cells.The MEM-143 is therefore not neuraminidase sensitive. The reactivity of This antibody can be blocked by a peptide including amino acids 79-88. |
| Reactivity: | Human |
| Applications: | Flow Cyt |
| Shipping condition: | Blue Ice |
| Publications: | Collagen-mediated survival signaling is modulated by CD45 in Jurkat T cells.Bijian K, Zhang L, Shen SH. Mol Immunol. 2007 Jul;44(15):3682-90. Epub 2007 May 23. |