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Data sheet of LAT monoclonal antibody, clone LAT-01
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Mouse |
| Applications | WB,IP,Flow Cyt |
More info about LAT monoclonal antibody, clone LAT-01
| Brand: | Abnova |
| Reference: | MAB3865 |
| Product name: | LAT monoclonal antibody, clone LAT-01 |
| Product description: | Mouse monoclonal antibody raised against partial recombinant LAT. |
| Clone: | LAT-01 |
| Isotype: | IgG1 |
| Gene id: | 27040 |
| Gene name: | LAT |
| Gene alias: | LAT1|pp36 |
| Gene description: | linker for activation of T cells |
| Immunogen: | Recombinant protein corresponding to cytoplasmic region of human LAT. |
| Form: | Liquid |
| Recommend dilutions: | The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS, pH 7.4 (0.09% sodium azide) |
| Storage instruction: | Store at 4°C. Do not freeze. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Antigen species / target species: | Human |
| Specificity: | This antibody reacts with Linker for activation of T cells (LAT), a 36-38 KDa transmembrane adaptor protein expressed by T cells, pre-B cells, NK cells, mast cells and platelets. |
| Reactivity: | Human |
| Application image: |  |
| Application image note: | Flow Cytometry analysis of LAT expression in human peripheral blood lymphocytes (PBL) using LAT monoclonal antibody, clone LAT-01 (Cat # MAB3865) (surface markers were stained prior to intracellular staining of human LAT). Panel A : gate on CD4+ cells. Panel B : gate on CD8+ cells. |
| Applications: | WB,IP,Flow Cyt |
| Shipping condition: | Blue Ice |
| Publications: | LAT and NTAL mediate immunoglobulin E-induced sustained extracellular signal-regulated kinase activation critical for mast cell survival.Yamasaki S, Ishikawa E, Sakuma M, Kanagawa O, Cheng AM, Malissen B, Saito T. Mol Cell Biol. 2007 Jun;27(12):4406-15. Epub 2007 Apr 9. |