| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Dog,Human,Monkey,Mouse,Rat |
| Host species | Rat |
| Applications | WB,IP,WB-Ce |
| Brand: | Abnova |
| Reference: | MAB3485 |
| Product name: | CASP2 monoclonal antibody, clone 11B4 |
| Product description: | Rat monoclonal antibody raised against partial recombinant CASP2. |
| Clone: | 11B4 |
| Isotype: | IgG2a |
| Gene id: | 835 |
| Gene name: | CASP2 |
| Gene alias: | CASP-2|ICH-1L|ICH-1L/1S|ICH1|NEDD2 |
| Gene description: | caspase 2, apoptosis-related cysteine peptidase |
| Immunogen: | Recombinant protein corresponding p19 subunit of human CASP2. |
| Form: | Liquid |
| Recommend dilutions: | Western Blot (2 ug/mL) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS (0.02% sodium azide) |
| Storage instruction: | Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Rat |
| Antigen species / target species: | Human |
| Specificity: | Recognizes an epitope in the p19 subunit of human, mouse, rat, monkey and dog caspase-2. Detects bands of ~51 KDa (procaspase-2), ~32 KDa and ~18 KDa (cleavage products) by Western blot. |
| Reactivity: | Dog,Human,Monkey,Mouse,Rat |
| Application image: | ![]() |
| Application image note: | Detection of pro-CASP2 (p51) , an intermediate cleavage product of CASP2 (p32) and activated CASP2 (p19) in FDC-P1 cells (mouse IL-3 dependent promyelocytic line) during growth factor with drawal induced apoptosis. Activation of CASP2 is inhibited in the presence of the caspase inhibitor Z-VAD-FMK. |
| Applications: | WB,IP,WB-Ce |
| Shipping condition: | Dry Ice |