| Product description: | Mouse monoclonal antibody raised against native PRKDC. |
| Clone: | 18-2 |
| Isotype: | IgG1 |
| Gene id: | 5591 |
| Gene name: | PRKDC |
| Gene alias: | DNA-PKcs|DNAPK|DNPK1|HYRC|HYRC1|XRCC7|p350 |
| Gene description: | protein kinase, DNA-activated, catalytic polypeptide |
| Immunogen: | Native purified PRKDC from HeLa cells. |
| Form: | Liquid |
| Recommend dilutions: | Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In 10 mM PBS, pH 7.4 (0.09% sodium azide) |
| Storage instruction: | Store at 4°C. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Specificity: | Reacts with the 460 KDa catalytic subunit of DNA-dependent Protein Kinase (DNA-PKcs). Inhibits kinase activity of DNA-PKcs ~50%, but preincubation of enzyme with DNA protects DNA-PKcs from inactivation by clone 18-2. In Western blot, clone 18-2 reacts with intact DNA-PKcs as well as its degradation products. |
| Size: | 100 ug |
| Shipping condition: | Blue Ice |